Cup holders Arsenal out after Gabriel own goal
Brazilian defender Gabriel conceded an own goal in the 24th minute, after a shot from Southampton defender Kyle Walker-Peters deflected into the net from his boot.
Southampton have now advanced to the fifth round, where they will travel to Wolverhampton Wanderers who on Friday knocked out sixth-tier side Chorley 1-0.
There are seven more FA Cup fixtures on Saturday with Manchester City visiting fourth-tier League Two side Cheltenham Town in a late kick-off match.(dpa/NAN)